Free essay: experiment 4: synthesis of salicylic acid from wintergreen oil abstract: the purpose of this experiment is to take methyl salicylate (wintergreen. Salicylic acid + acetic anhydride → aspirin + h 2 o o oh oh salicylic acid o o h 3 c o ch 3 acetic anhydride each molecule of acetic anhydride forms two molecules of acetic acid in its reaction with water. Carbon 4 synthesis of aspirin from salicylic acid salicylic acid acetic anhydride sodium acetate acetylsalicylic acid acetic acid molecular mass 13812 g mol-1 10209 g mol-1 8203 g mol-1 18016 g mol-1 6005 g mol-1.
Synthesis of acetylsalicylic acid occurs by protonation of carbonyl (c=o) group, and a nucleophilic attack of oh on the acetic anhydride discussion - in this synthesis, methyl salicylate is the starting material or precursor and salicylic acid is the target product salcyclic acid synthesis discussion. Chan 1 introduction acetyl salicylic acid, commonly known as aspirin, is one of the most common synthetic medicines first discovered in 1897 by felix hoffman, it has since been used in over 50 over-the-counter medicines. Learn how to synthesize aspirin from salicylic acid get information about the effects of salicylates, and see the structures of the reactants first, gather the chemicals and equipment used to synthesize the aspirin aspirin synthesis materials.
Synthesis of salicylic acid from wintergreen oil abstract: the purpose of this experiment is to take methyl salicylate (wintergreen oil) and by heating it discussion: reaction oh o och3 2) h2so4 1) 2naoh oh o oh 1 595 ml methyl salicylate is reacted with. We will synthesize salicylic acid (a precursor to aspirin) to determine if the environmentally friendly synthesis produces a superior aspirin product compared to the industrial synthesis from benzene. Synthesis of salicylic acid from wintergreen oil abstract: the purpose of this experiment was to break down methyl salicylate into salicylic acid this process was accomplished by breaking down methyl salicylate into disodium salicylate and then breaking that down to. 42 experiment 8 - synthesis of aspirin aspirin is an effective analgesic (pain reliever), antipyretic (fever reducer) and anti-inflammatory agent and is one of the most widely used non-prescription drugs.
Synthesis of acetylsalicylic acid (aspirin) aini ag (2012xxxxxx) 190313 (tues) abstract acetylsalicylic acid was obtained from esterification reaction between salicylic acid and acetic anhydride in 9740% yield. The kolbe synthesis for the production of salicylic acid was created by the german chemist hermann kolbe in this process, sodium phenoxide is heated with carbon dioxide under pressure (100 atm) and the mixture is then acidified to yield salicylic acid. Synthesis of acetylsalicylic acid through esterification helen rowi m tolentino, jose angelo s trinidad, maria cherisse p results and discussion salicylic acid round filter paper pre-weighed square filter paper post-weighed square filter paper actual yield.
A student researched lab analysis about the synthesis of salicylic acid from wintergreen oil my yield for the production of salicylic acid was 569% this was due majorly for the fact that the filteration system on many of the suction faucets did not work. Discussion in the experiment salicylic acid synthesized from two different materials, wintergreen oil and benzene were compared firstly the acid was synthesizing from the wintergreen oil by heating through reflux using sodium hydroxide. The synthesis and analysis of aspirin table 1: synthesis of aspirin mass of salicylic acid used (g) 2015 g volume of acetic an-hydride used (ml) 500 ml. In a 500 ml round-bottomed flask, a mixture of 304 g of salicylic acid (02 mole), 70 ml of methyl alcohol, and 7 ml of concentrated sulfuric acid are is placed a boiling chip is added, a reflux condenser is attached, and the mixture is boiled gently on the steam bath for 5-7 hours.
In each of your two equations, label the reacting part of salicylic acid as either acid or alcohol discussion: in a well-organized paragraph, discuss potential contaminants to your aspirin product. Salicylic acid (from latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (bha) it has the formula c7h6o3 this colorless crystalline organic acid is widely used in organic synthesis and functions as a plant. Salicylic acid (sa) has been shown to regulate various aspects of growth and development it also serves as a critical signal for activating disease resistance in arabidopsis thaliana and other plant species this review surveys the mechanisms involved in the biosynthesis and metabolism of this. Acetyl salicylic acid synthesis ciba hs institute an inspection of the structural formula of salicylic acid shows that the molecule consists of the following three units: phenol group benzene ring and hydroxyl group 2 carboxylic acid group.